PCBs and tight junction expression
نویسندگان
چکیده
منابع مشابه
Enterotoxigenic Escherichia coli infection induces tight junction proteins expression in mice
Enterotoxigenic Escherichia coli (ETEC) causes diarrhea in travelers, young children and piglets, but the precise pathogenesis of ETEC induced diarrhea is not fully known. Recent investigations have shown that tight junction (TJ) proteins and aquaporin 3 (AQP 3) are contributing factors in bacterial diarrhea. In this study, using immunoblotting and immunohistochemistry analyses, we found that E...
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The molecular mechanisms by which Ca 2 1 and metal ions interact with the binding sites that modulate the tight junctions (TJs) have not been fully described. Metal ions were used as probes of these sites in the frog urinary bladder. Basolateral Ca 2 1 withdrawal induces the opening of the TJs, a process that is abruptly terminated when Ca 2 1 is readmitted, and is followed by a complete recove...
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The tight junction is an important subcellular organelle which plays a vital role in epithelial barrier function. Claudin, as the integral membrane component of tight junctions, creates a paracellular transport pathway for various ions to be reabsorbed by the kidneys. This review summarizes advances in claudin structure, function and pathophysiology in kidney diseases. Different claudin species...
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Tight junction plays a critical role in intestinal defence. The alteration and perturbation of tight junction proteins could induce intestine barrier damage, and lead to the malabsorption of electrolytes and water. Previous studies had showed that colonic infection and inflammation could lead to the alteration of tight junction function, and somatostatin could protect intestinal epithelia. Thus...
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Introduction: Several attempts to invent implantable devices have done, and it is also necessary to develop biocompatible packaging materials for implantable devices. Thus, we evaluated the biocompatibility of polydimethylsiloxane (PDMS) and polymethyl methacrylate (PMMA) by analyzing of the changes of macrophage, macrophage migratory inhibitory factor (MIF) and inflammatory cytokines of the bl...
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ژورنال
عنوان ژورنال: Environmental Toxicology and Pharmacology
سال: 2008
ISSN: 1382-6689
DOI: 10.1016/j.etap.2007.10.019